SIDER contains information on marketed medicines and their recorded adverse drug reactions. The information is extracted from public documents and package inserts. The available information include side effect frequency, drug and side effect classifications as well as links to further information, for example drug–target relations.
The SIDER Side Effect Resource represents an effort to aggregate dispersed public information on side effects. To our knowledge, no such resource exist in machine-readable form despite the importance of research on drugs and their effects. The creation of this resource was motivated by the many requests for data that we received related to our paper (Campillos, Kuhn et al., Science, 2008, 321(5886):263-6.) on the utilization of side effects for drug target prediction. Inclusion of side effects as readouts for drug treatment should have many applications and we hope to be able to enhance the respective research with this resource.
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SIDER Side Effect Resource
Here, you can download the current version of SIDER 4.1, which has been released on October 21, 2015. This and previous versions can be found on the FTP site. Compared to the version released on August 6, 2015, this version uses side effect names from MedDRA in the download files.
License: Except as otherwise noted, this work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License. For commercial use or customized versions, please contact biobyte solutions GmbH.
Disclaimer: The content of this database of side effects (adverse drug reactions) is intended for educational and scientific research purposes only. It is not intended as a substitute for professional medical advice, diagnosis or treatment.